After adjusting for age, gender, PD vintage, residual renal function, hypertension, hyperlipidemia, alkaline phosphatase, calcium-phosphorus product, and calcium carbonate and active vitamin D use, log-FGF23 (β: 0.61, 95% confidence interval: 0.06–1.16, p = 0.029) was an independent predictor of aortic PWV in patients with DM but not in those without (β: 0.10, 95% confidence interval: − 0.24–0.45, p = 0.546). Here, FGF23 is linked to hypertensive disorder.