Different populations of T-cells, identified by cell surface protein marker expression, were analyzed by unbiased clustering analysis using single cell mass cytometry (CyTOF) in tumors from CT26 TB mice (a T-cell rich tumor model) treated with ceralasertib alone or in combination with anti-PD-L1 after one 7-days on/7-days off cycle (Fig. 3a). Here, CD274 is linked to neoplasm.