Moreover, the susceptibility of hs-cTnT 99th percentiles to diabetes than hs-cTnI, the non-interchangeable role of hs-cTnI with hs-cTnT in diabetic CVD risk stratification, and the different pattern in correlations with CVD risk factors between hs-cTnT and hs-cTnI across glycemic status suggested elevated hs-cTnT and hs-cTnI may be associated with different pathological processes in the context of chronic hyperglycemia. The gene discussed is TNNI3; the disease is diabetes mellitus.