Based on univariate analyses, the risk of stroke was not related to BUN and HGB(P > 0.05), but was positively correlated with age, PLT, Scr, TC, TG, LDL-c, CRP, HBA1C, UA, Cystain C, FPG, hypertension, DM and current drinking, current smoking, whereas it was negatively associated with HDL-c and eGFR (all P < 0.05) (Additional fil 1: Table S2). This evidence concerns the gene CRP and Stroke.