Three models were used: Model I (not adjusted for any covariates), Model II (adjusted for sex and age), Model III (adjusted for age, CRP, eGFR, sex; HDL-c, LDL-c, UA, CLD, PLT, Cystatin C; hypertension, HBA1C, diabetes; CKD, smoking, and drinking status variables). This evidence concerns the gene CRP and chronic kidney disease.