In our study, there were missing data on BUN (1, 0.01%), smoking status (1, 0.01%), Scr (2, 0.02%), HDL-c (2, 0.02%), alcohol consumption (4, 0.05%), LDL-c (13, 0.15%), CLD (30, 0.34%), CKD (41, 0.47%), hypertension (46, 0.53%), DBP (61, 0.70%), HBA1c (62, 0.71%), DM (82, 0.94%), SBP (93, 1.06%), PLT (165, 1.90%), HGB (166, 1.91%), WBC (169, 1.94%), cystatin C (2090, 24.03%), and eGFR (2, 0.02%). This evidence concerns the gene CST3 and chronic kidney disease.