It also participates in gene fusions in myeloid or lymphoid neoplasms associated with eosinophilia, with FIP1L1::PDGFRA the most common fusion.4PDGFRA amplification may also play a role in the oncogenesis of intimal sarcomas and undifferentiated cardiac sarcomas.5 The gene discussed is FIP1L1; the disease is intimal sarcoma.