JAM3 and breast cancer: On the one hand, it was clear that all 16 genes had considerably lower expression levels in BC tissues than in normal tissues in our GEO cohort, on the other hand, the accuracy of these genes as diagnostic genes was quite high, with all AUC values of more than 0.79, including JAM3 (Figure S1G and S1H, Supplementary material 1 and 2).