PPY and neoplasm: The pancreatic polypeptide (Ppy) gene was the top significantly down-regulated gene in FMT-MI tumour tissues (log2(fold change) (log2FC) = −0.605, padj = 0.0144), followed by the Rho family GTPase 2 (Rnd2) gene (log2FC = −0.518, padj = 0.029) (Figure 3A).