Based on the classification of immune subtypes from immunogenomics analysis of TCGA data,47 AGC's IFN‐γ dominant subtype is characterized by the lowest Th1/Th2 ratio, a high proliferation rate, and the highest intratumoral heterogeneity, while RCC's inflammatory subtype demonstrates the opposite trend: a high Th1/Th2 ratio, low proliferation rate, and the lowest intratumoral heterogeneity. Here, IFNG is linked to renal cell carcinoma.