NSD2 mediates the proliferation and apoptosis of tumor cells by regulating the expression of tumor‐related cytokines, such as tumor necrosis factor alpha (TNF‐α), interleukin 6 (IL‐6), IL‐8, and vascular endothelial growth factor A, or by reducing p53 stability.14, 15. Here, IL6 is linked to neoplasm.