The top five pathways associated with the acute stage of infection were cytokine–cytokine receptor interaction, TNF signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase-AKT (PI3K-AKT) signaling pathway, mitogen-activated protein kinase (MAPK), and NOD-like receptor signaling. This evidence concerns the gene WNK2 and infection.