Still, the authors argue that an excess of plasma leptin has a negative impact on testosterone-producing Leydig cells’ function and decreases the plasma testosterone level [18], and it is suggested that the local environment of hair follicles can be affected and have an impact on the local production of testosterone and dihydrotestosterone, which has implications for the development of androgenetic alopecia [18]. Here, LEP is linked to androgenetic alopecia.