ADAMTS-13 deficiency is associated with thrombotic thrombocytopenic purpura (TTP), although there is growing evidence that it is implicated in many other conditions, such as ischemic stroke, myocardial infarction, sepsis, and perioperative thrombotic complications in neonates and infants [7]. This evidence concerns the gene ADAMTS13 and thrombotic thrombocytopenic purpura.