As for ESKD, the univariate analysis identified age, male sex, a higher Charlson comorbidity index, the presence of diabetes mellitus, hypertension, lower eGFR, increased proteinuria, higher triglycerides, lower serum albumin, higher uric acid, an increased MEST-C score, and the absence of RASI as significantly associated factors. The gene discussed is ALB; the disease is Hypertension.