NLRP3 and pericarditis: Intriguingly, Mauro et al. have recently proved that inflammasome NLRP3 and IL-1 are inflammation culprits in RP pathogenesis, highlighting the role of NLRP3 both in human and in murine pericarditis, as well as the better response of murine-induced pericarditis to drugs antagonizing the NLRP3 pathway [28].