A specific type of lipid disorder, usually associated with obesity, metabolic syndrome, type 2 DM or prediabetes, is the atherogenic dyslipidaemia, characterised by increased plasmatic levels of both fasting and postprandial triglycerides (TGs), low levels of high-density lipoprotein cholesterol (HDLc) and apolipoprotein A1 (ApoA1), the increase of small, dense low-density lipoprotein (LDL) particles and of the lipoproteins that contain apolipoprotein B (apo B), parameters that have been independently associated with a higher CV risk [14,15]. Here, APOA1 is linked to obesity due to melanocortin 4 receptor deficiency.