The upregulation of RFC4 was observed to be statistically significant in many cancer types, such as BLCA, BRCA, CHOL, COAD, ESCA, GBM, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, READ, STAD, and UCEC (p < 0.001), and CESC (p < 0.01, Figure 2A). Here, RFC4 is linked to cancer.