A self-assembling EGFR-targeting peptide was conjugated with an AIEgen to yield TPA-FFG-LA to form nano-assemblies on the surface of EGFR-positive triple-negative breast cancer (TNBC) cells, which inhibit EGFR signaling and trigger lysosomal membrane permeabilization (LMP) after being internalized into the cells [69]. Here, EGFR is linked to triple-negative breast carcinoma.