SLC1A5 and Familial prostate cancer: One important role for ASCT2 in the progression of cancer is its function as a high-affinity Gln transporter supplying the Gln-addicted cancer cells as has been demonstrated in NSCLC, prostate cancer, triple-negative breast cancer, head and neck squamous cell carcinoma, and oral squamous cell carcinoma cells [60,61,62,63,64].