The p21 level of colon cancer tissue was the lowest (cancer, 10.122 vs. normal, 11.050), followed by lung cancer (cancer, 10.204 vs. normal 10.543) and breast cancer (cancer, 9.550 vs. normal 9.667) with log2 (transcripts per million, TPM). This evidence concerns the gene CDKN1A and malignant colon neoplasm.