To determine when animals exhibited a phenotype consistent with prediabetes and to evaluate the impact of BJ supplementation on glucose tolerance and insulin sensitivity, we monitored prediabetic rats glycemic (GTT) and insulinemic (ITT) profile every 8 weeks, over the 24-week study period, and assessed fasting and postprandial glucose and insulin levels at the end of the study (Figure 2). This evidence concerns the gene INS and prediabetes syndrome.