In mice, Foxp3 gene mutation results in the scurfy (SF) mouse model, which serves as a unique model for a rapidly fatal disease characterized by immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (human IPEX syndrome [5,6,7]. This evidence concerns the gene FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.