Studies on the relationship between the MPV value and certain biological (presepsin, NT-proBNP, red cell distribution width (RDW)), echocardiographic (left ventricle ejection fraction (LVEF), left atrium (LA) dimensions, left ventricle (LV) dimensions, presence of pulmonary hypertension (PH)), and electrocardiographic (sinus rhythm (SR), atrial fibrillation (AFib) rhythm) parameters in groups of subjects with HF are limited. This evidence concerns the gene NPPB and pulmonary hypertension.