IL1A and colonic neoplasm: Importantly, recent evidence suggest that extracts and isolated compounds from Vitis vinifera elicit anticancer activity via distinct underlying mechanisms including activation of the immune system in colon cancer cells, suppressing metastasis in aggressive breast cancer via downregulation of interleukin 1 alpha (IL-1α), and affecting gene expression of fatty acid-binding protein 5 (FABP5) to block the proliferation of prostate cancer cells [23,24,25].