IL3 and lymphoma: Another in vitro study, conducted by Calviño and colleagues, evaluated the effect of two aqueous extracts (E1, unboiled, obtained after centrifugation of fruiting bodies in sterile water at room temperature for 5 min; E2, boiled, obtained by resuspending the pellet in sterile water and boiling for 5 min) and a methanolic extract (E3, obtained after fruiting bodies were disrupted and resuspended in 10% ethanol; the solvent evaporated, and the compound was resuspended in dimethyl-sulfoxide) of G. lucidum on a murine model of interleukin-3 (IL-3)-modulated lymphoma, lymphoma DA-1 cells.