LPA and peripheral arterial disease: Poller et al. followed 10 patients with severe PAD and elevated levels of Lp(a) who had undergone previous revascularization procedures; the primary endpoint of the study was to analyze the rate of new procedures of revascularization in the following 12 months compared with the previous 24 months before apheresis; the secondary endpoints were related to the impact of such a treatment approach on the clinical symptoms of PAD (pain, walking distance) [47].