GPT and chronic hepatitis: The natural history of CHB includes five main phases, (1) HBeAg-positive chronic infection, (2) HBeAg-positive chronic hepatitis, (3) HBeAg-negative chronic infection, (4) HBeAg-negative chronic hepatitis, and (5) HBsAg-negative phase, accounting for HBeAg status, HBV DNA levels, ALT, and liver Inflammation [5].