Reyes-Pardo et al. [50] showed also that empagliflozin (10 mg/kg/day) treatment for two weeks attenuated oxidative stress, proteinuria, and glomerular filtration rate reduction associated with angiotensin II infusion; thereby, reducing kidney damage development in a rat model of angiotensin II-dependent kidney damage. The gene discussed is AGT; the disease is Nephropathy.