To elucidate the heterogeneity of PLAUR in tumor cells, we first defined the cell types of the published single-cell sequencing data and then extracted the tumor cell population and classified it into four single-cell states (AC-like, OPC-like, NPC-like, MES-like), based on the study of Neftel et al., and discovered that PLAUR was markedly overexpressed in the MES-like subgroup, which agreed with the bulk sequencing results. The gene discussed is PLAUR; the disease is neoplasm.