TNFRSF8 and mature T-cell and NK-cell non-Hodgkin lymphoma: The ECHELON-2 trial was designed to compare the efficacy and safety of BV in combination with Cyclophosphamide, Doxorubicin, and Prednisone (A+CHP) to standard CHOP (Cyclophosphamide, Adriamycin, Vincristine, and Prednisone) for the treatment of previously untreated patients with CD30-positive PTCL.