There were no significant associations between CHK2 and p53 expression levels and sex, age at diagnosis, tumor size, histopathological subtypes, multifocality, lymph node (LN) metastases, distant metastases, extrathyroidal extension, vascular invasion, margin status, higher clinical stage of cancer, and intermediate and high recurrence or I-131 treatment. Here, CHEK2 is linked to cancer.