The univariable predictors included heart rate > 110 (beats/min) (OR = 2.56; 95% CI 1.02–6.42; p = 0.046), respiratory rate > 22 (breaths/min) (OR = 5.17; 95% CI 1.63–16.4; p = 0.005), hematemesis (OR = 11.1; 95% CI 1.45–85.2; p = 0.021), active bleeding (OR = 13.5; 95% CI 4.73–38.2; p < 0.001), previous stent implantation (OR = 5.76; 95% CI 2.01–16.5; p = 0.001), Hb < 8 (g/dL) (OR = 3.93; 95% CI 1.54–10.0; p = 0.004), PT > 13 (s) (OR = 3.31; 95% CI 1.30–8.39; p = 0.012), and serum creatinine level > 1.2 (mg/dL) (OR = 3.95; 95% CI 1.52–10.2; p = 0.005). The gene discussed is GSTM1; the disease is Hematemesis.