In an available gene expression dataset from tumor specimens of HNSCC patients treated with primary radio/chemotherapy (n = 137, DKTK-ROG) [23], we analyzed the clinical potential of KDM6A (UTX) and KDM6B (JMJD3) as putative prognostic biomarkers and stratified patients into high and low expression groups based on median gene expression values. Here, KDM6B is linked to neoplasm.