Univariate analysis revealed that high expression of METTL14, RBM15, ZC3H13, WTAP, FTO, ALKBH5, YTHDF1, YTHDF2, YTHDF3, YTHDC1, YTHDC2, IGF2BP2, and IGF2BP3 was associated with an unfavorable prognosis for gliomas. This evidence concerns the gene YTHDF2 and central nervous system cancer.