TNBC is a subtype of breast cancer characterized by certain distinctive features, briefly summarized in the following [26]: (1) TNBC does not express the three specific receptors commonly found in breast cancer cells: estrogen receptors (ERs), progesterone receptors (PRs), and human epidermal growth factor receptor 2 (HER2/neu). The gene discussed is ESR1; the disease is breast carcinoma.