L1CAM and cancer: Overall, the more pronounced invasive capacity of the Panc1 Holoclone cells, along with the elevated expression of mesenchymal proteins like Vimentin [99,100,101,102,103,104] and L1CAM [89,105,106,107], which have been associated with an increased invasive potential in a variety of cancers like PDAC, are clearly in line with the highest number of microscopic tumoral lesions detected in vivo.