Fuentes-Fayos et al. demonstrated inhibition of SF3B1 bring about significant alterations within the AKT-mTOR and ß-catenin signalling pathways which is closely associated with glioblastoma (GBM) progression and initiation while also having direct involvements with autophagy regulations suggestive of changes in SF3B1 can influence GBM through autophagic pathways [55,56]. Here, AKT1 is linked to glioblastoma.