For instance, it has been shown that an elevated glycolysis-derived lactate level could accelerate histone 3 lysine 9 lactylation (9H3K9la) at the promoter of solute carrier family 7 member 11 (SLC7A11) and confer microglial activation and neuroinflammation by increasing its transcription in Parkinson’s disease [89]. This evidence concerns the gene SLC7A11 and Parkinson disease.