Dystrophin, a monomeric 427-kDa cytoskeletal protein encoded by the X-chromosome located Duchenne muscular dystrophy (DMD) gene, is part of the β-spectrin/α-actinin protein family, which shares a common structural pattern, including an actin-binding domain at the NH2 terminus, followed by a variable number of spectrin-like repeats [21,22,23]. Here, DNM2 is linked to Duchenne muscular dystrophy.