Serum IL-6 was significantly increased in both groups, CKD and ESKD, as compared to the controls (p < 0.01, respectively), and the same applied for IL-8 (p < 0.05, p < 0.001, respectively) and IL-10 (p < 0.001, p < 0.01, respectively). The gene discussed is CXCL8; the disease is chronic kidney disease.