From these findings, we noted that Centromere Protein F (CENPF), Marker of proliferation Ki-67 (MKI67), Poly (ADP-Ribose) Polymerase Family Member 14 (PARP14), and Transcriptional Repressor GATA Binding 1 (TRPS1) were consistently upregulated in IPAH patients, while 38 other genes showed no significant statistical difference (Table 4). The gene discussed is CENPF; the disease is idiopathic pulmonary arterial hypertension.