The platelet count and prothrombin time decreased, while the aspartate aminotransferase (AST), alanine aminotransferase (ALT), high density lipoprotein (HDL), FIB-4 score, and APRI score increased with more advanced stages of liver disease (p < 0.05 for all analyses using the Mann–Whitney U test, Table 1). Here, F2 is linked to liver disorder.