With regard to selected malignancies, SNPs within the IL-8 gene have been shown to decrease the risks of hepatocellular [35,43] and nasopharyngeal carcinomas [44], and to increase the susceptibility to gliomas [45] and osteosarcomas [46], as well as gastric [47], lung [48,49], prostate [50], and some subsets of breast carcinomas [51,52,53]. The gene discussed is CXCL8; the disease is breast carcinoma.