In mice with fatty liver and graft injury, arachidonic acid can activate nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome in MDSCs through fatty acid transport protein 2 (FATP2), which can increase IL-17 production in CD4+ T cells to cause tumor recurrence [51]. This evidence concerns the gene SLC27A2 and neoplasm.