LEP and obesity due to melanocortin 4 receptor deficiency: However, the levels of leptin showed a differentiated pattern, with the lowest values in the healthy normal-weight women (1.6 (0.6–3.2); p = 0.007, compared to other nutritional states in healthy women) and the highest values in the group with breast cancer and obesity (12.23 (15.31) ng/mL; p = 0.014, compared to other nutritional states in women with breast cancer, see Table 4).