Given the pivotal role of SLC7A11 in disulfidoptosis mechanisms and its significant differential expression, as highlighted above, we sought to validate the disulfidoptosis-related cell death activity in these tumor types by assessing the expression levels of SLC7A11 in three cancer cell lines and their normal counterparts using qRT-PCR and Western blot analyses. The gene discussed is SLC7A11; the disease is neoplasm.