Utilizing CCK-8 assays, we assessed the role of SLC7A11 in the proliferation of hepatocellular carcinoma cell lines, SNU449 and Huh7, post-transfection with si-SLC7A11-1 and -2, and a notable decline in proliferation rates was observed when compared to the blank control over 120 h, initiating 48 h following transfection (p < 0.05; Figure 9C). The gene discussed is SLC7A11; the disease is hepatocellular carcinoma.