The aberrantly expressed genes included neuropeptide Y, relaxin/insulin-like family peptide receptor 2, adrenoceptor beta 3, gonadotropin-releasing hormone 1, somatostatin, adrenoceptor beta 1, cholecystokinin, and neuropeptide B. Enrichment of the same pathway has also been reported in studies that investigated different types of pain, including neuropathic pain, paclitaxel-induced peripheral neuropathy, and chronic compression injury pain [62,63,64]. Here, ADRB1 is linked to peripheral neuropathy.