LRRK2 and Parkinson disease: Autosomal dominant PD inheritance is linked to mutations in genes encoding α-synuclein (SNCA or Park1/4), leucin-rich-repeat kinase 2, LRRK2 (Park8), and VPS35 retromer complex component (Park17), while autosomal recessive PD forms are due to mutations in Parkin (Park2), PTEN-induced kinase 1, PINK1 (Park6), and DJ-1 (Park7) genes.