The elevated levels of CAT, SOD, and GSH-Px are vital in converting ROS into less harmful compounds and consequently reducing ROS-mediated damage on DNA and entire chromosomes, amino acid modification, contribution to protein fragmentation, lipid peroxidation intensification in cell membranes, and cell apoptosis and necrosis which increase the risk of inflammations and cancer [99,101,102]. The gene discussed is SOD1; the disease is cancer.