ABCB1 and lung cancer: It was also found that lung cancer cell sublines No. 15-80-1 and No. 15-80-6, which are obtained when treating the NCI-H460 cell line with increasing doses of the inducer Pgp paclitaxel (from 50 to 800 nM), are characterized by amplification of the MDR1 gene with a different number of copies.