A few single-nucleotide variants (SNVs) in TERT, RTEL1, and NAF1 genes are reported to associate with long telomeres [18,19], suggesting that they may be associated with an increased risk of cancer, as shown for rs2736100 in the TERT gene that is associated with an increased risk of adenocarcinoma [19]. The gene discussed is TERT; the disease is cancer.